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Motzer RJ. N Engl J Med 2013;369(8):722.

Adverse Event

1

Pazopanib

(n = 554) %

Sunitinib

(n = 548) %

All Grades

All Grades

Any event

2

>99

>99

Diarrhea

63

57

Fatigue

55

63

Hypertension

46

41

Nausea

45

46

Decreased appetite

37

37

ALT increased

31

18

Hair color changes

30

10

Hand-foot syndrome

29

50

Taste alteration

26

36

Thrombocytopenia

10

34

Pazopanib

Pazopanib

COMPARZ: fase III.

PAZOPANIB: ENSAYOS CLÍNICOS.