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J Clin Oncol 36. © 2018 by American Society of Clinical Oncology
• Prosigna can reliably identify node-
negative patients and a significant
proportion of patients with one to
three positive nodes who can be
spared adjuvant chemotherapy.
• Population-based Danish Breast
Cancer Cooperative Group
database (2000 through 2003)
• Operable breast cancer patients
treated with endocrine therapy alone
selected
• 2,726 (99.5%) passed the PAM50
quality assessment.