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FIRSTANA: Diseño

159 centers worldwide

CBZ 20 + PRED

Cabazitaxel 20 mg/m² Q3W

+ prednisone 10 mg/d

n = 389

mCRPC and no prior

chemotherapy

N = 1,168 pts

R

A

N

D

O

M

I

Z

E

CBZ 25 + PRED

Cabazitaxel 25 mg/m² Q3W

+ prednisone 10 mg/d

n = 388

DOC + PRED

Docetaxel 75 mg/m² Q3W

+ prednisone 10 mg/d

n = 391

Oudard S et al. J Clin Oncol: 2017; 35:3189-3197.