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INTRODUCCIÓN

Adapted from Halabi S,

J Clin Oncol

2009;27: 2766-2771.

Median Follow-Up of > 4 Years

p = 0.0002

p < 0.0001

p = 0.005

p < 0.0001

p < 0.0001

p = 0.0033

Primary Endpoints: rPFS and OS

Secondary Endpoints

PSA

Progression

Death

ECOG PS Decline

Chemotherapy

Baseline

Tumor/Bone

Progression

Pain

Ryan C et al. ESMO 2014; Abstract 7530 (oral presentation)