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Exposure to relapse treatments after FFS event

Note:

Randomisation:

Nov-2011 to Jan-2013

Data freeze:

Feb-2017

Docetaxel started after FFS event

AR-targeted therapy started after FFS event

SOC+AAP

SOC+DocP

FFS event

FFS event

Note:

Relapse treatments at investigators’ discretion

Access to relapse treatments may depend on:

Metastatic status at event

Calendar year of event

Suspect under reporting of third-line therapies and onwards

SOC+AAP

SOC+DocP

Courtesy of Matt Sydes. ESMO 2017